Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21(Waf/Cip1) stabilization by activating the ERK1/2-MAPK pathway.

Zhang, Yonglong; Liu, Yanfeng; Duan, Jinlin; Yan, Haibo; Zhang, Jun; Zhang, Huilu; Fan, Qi; Luo, Feifei; Yan, Guoquan; Qiao, Ke; Liu, Jie

Zhang, Yonglong; Liu, Yanfeng; Duan, Jinlin; Yan, Haibo; Zhang, Jun; Zhang, Huilu; Fan, Qi; Luo, Feifei; Yan, Guoquan; Qiao, Ke; Liu, Jie.

Afiliação

Zhang Y; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Liu Y; Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.
Duan J; Department of Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Yan H; Key Laboratory of Medical Molecular Virology (MOE & MOH), Shanghai Medical College, Fudan University, Shanghai, China.
Zhang J; Department of Pathology, Affiliated Tongren Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Zhang H; Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.
Fan Q; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Luo F; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Yan G; Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Qiao K; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Liu J; Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.

Hepatology ; 63(3): 880-97, 2016 Mar.

Article em En | MEDLINE | ID: mdl-26659654

Assuntos

Carcinoma Hepatocelular/metabolismo; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Neoplasias Hepáticas/metabolismo; Neurocalcina/metabolismo; Animais; Estudos de Casos e Controles; Ciclo Celular; Linhagem Celular Tumoral; Células HEK293; Humanos; Marcação por Isótopo/métodos; Sistema de Sinalização das MAP Quinases; Masculino; Camundongos Endogâmicos BALB C; Camundongos Nus; Transplante de Neoplasias; Proteínas Nucleares/metabolismo; Proteômica/métodos; Proteínas Quinases Associadas a Fase S/metabolismo; Ubiquitina-Proteína Ligases/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neurocalcina / Inibidor de Quinase Dependente de Ciclina p21 / Neoplasias Hepáticas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Hepatology Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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