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[Forensic Investigation of Goldeneye™ DNA ID 22NC Kit].
Fa Yi Xue Za Zhi ; 31(4): 280-3, 2015 Aug.
Article em Zh | MEDLINE | ID: mdl-26665881
OBJECTIVE: To investigate the genetic data of 21 autosomal STR included in Goldeneye™ DNA ID 22NC Kit in Chinese Han nationality and to evaluate the forensic application. METHODS: By detected 500 unrelated healthy individuals in Chinese Han nationality of East China with Goldeneye™ DNA ID 22NC Kit, allele frequencies, population genetics parameters and linkage disequilibrium information of the 21 autosomal STR were statistically analyzed. RESULTS: In the 21 autosomal STR, no deviations from Hardy-Weinberg equilibrium were detected and all loci were independent form each other. DP values of 21 autosomal STR were all above 0.85, and the combined discrimination power was 1-3.616 5 x 10(-26). Combined mean exclusion chance of this system in duo cases was 1-2.786 81 x10(-6), in trio cases was 1-8.545 82 x 10(-1). CONCLUSION: Twenty-one autosomal STR included in Goldeneye™ DNA ID 22NC Kit are highly polymorphic in the Han nationality. Combined with Goldeneye™ DNA ID 20A Kit, the kit can satisfy the needs for full-sibling testing and facilitate the solution of this kind of case tools.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Povo Asiático / Genética Forense / Loci Gênicos Limite: Humans País/Região como assunto: Asia Idioma: Zh Revista: Fa Yi Xue Za Zhi Assunto da revista: JURISPRUDENCIA Ano de publicação: 2015 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Povo Asiático / Genética Forense / Loci Gênicos Limite: Humans País/Região como assunto: Asia Idioma: Zh Revista: Fa Yi Xue Za Zhi Assunto da revista: JURISPRUDENCIA Ano de publicação: 2015 Tipo de documento: Article