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Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.
He, Z; Leong, D J; Zhuo, Z; Majeska, R J; Cardoso, L; Spray, D C; Goldring, M B; Cobelli, N J; Sun, H B.
Afiliação
  • He Z; Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: zhiyong.he@einstein.yu.edu.
  • Leong DJ; Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: daniel.leong@einstein.yu.edu.
  • Zhuo Z; Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; China-Japan Union Hospital of Jilin University, Jilin, China. Electronic address: zhuo.zhang@einstein.yu.edu.
  • Majeska RJ; Department of Biomedical Engineering, The City College of New York, New York, NY 10029, USA. Electronic address: rmajeska@ccny.cuny.edu.
  • Cardoso L; Department of Biomedical Engineering, The City College of New York, New York, NY 10029, USA. Electronic address: cardoso@ccny.cuny.edu.
  • Spray DC; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: david.spray@einstein.yu.edu.
  • Goldring MB; Hospital for Special Surgery, New York, NY, USA. Electronic address: goldringm@hss.edu.
  • Cobelli NJ; Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: ncobelli@montefiore.org.
  • Sun HB; Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: herb.sun@einstein.yu.edu.
Osteoarthritis Cartilage ; 24(5): 892-901, 2016 May.
Article em En | MEDLINE | ID: mdl-26687824
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transativadores / Trifosfato de Adenosina / Condrócitos / Sinalização do Cálcio / Mecanotransdução Celular Limite: Animals / Humans / Male Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Transativadores / Trifosfato de Adenosina / Condrócitos / Sinalização do Cálcio / Mecanotransdução Celular Limite: Animals / Humans / Male Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2016 Tipo de documento: Article