Evaluation of upper airway collapsibility using real-time MRI.
J Magn Reson Imaging
; 44(1): 158-67, 2016 07.
Article
em En
| MEDLINE
| ID: mdl-26708099
ABSTRACT
PURPOSE:
To develop and demonstrate a real-time MRI method for assessing upper airway collapsibility in sleep apnea. MATERIALS ANDMETHODS:
Data were acquired on a clinical 3 Tesla scanner using a radial CAIPIRIHNA sequence with modified golden angle view ordering and reconstructed using parallel imaging and compressed sensing with temporal finite difference sparsity constraint. Segmented airway areas together with synchronized facemask pressure were used to calculate airway compliance and projected closing pressure, Pclose , at four axial locations along the upper airway. This technique was demonstrated in five adolescent obstructive sleep apnea (OSA) patients, three adult OSA patients and four healthy volunteers. Heart rate, oxygen saturation, facemask pressure, and abdominal/chest movements were monitored in real-time during the experiments to determine sleep/wakefulness.RESULTS:
Student's t-tests showed that both compliance and Pclose were significantly different between healthy controls and OSA patients (P < 0.001). The results also suggested that a narrower airway site does not always correspond to higher collapsibility.CONCLUSION:
With the proposed methods, both compliance and Pclose can be calculated and used to quantify airway collapsibility in OSA with an awake scan of 30 min total scan room time. J. Magn. Reson. Imaging 2016;44158-167.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Faringe
/
Processamento de Sinais Assistido por Computador
/
Imageamento por Ressonância Magnética
/
Interpretação de Imagem Assistida por Computador
/
Apneia Obstrutiva do Sono
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Magn Reson Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos