miR-215 promotes malignant progression of gastric cancer by targeting RUNX1.

Li, Na; Zhang, Qi-Yue; Zou, Jian-Ling; Li, Zhong-Wu; Tian, Tian-Tian; Dong, Bin; Liu, Xi-Juan; Ge, Sai; Zhu, Yan; Gao, Jing; Shen, Lin

Li, Na; Zhang, Qi-Yue; Zou, Jian-Ling; Li, Zhong-Wu; Tian, Tian-Tian; Dong, Bin; Liu, Xi-Juan; Ge, Sai; Zhu, Yan; Gao, Jing; Shen, Lin.

Afiliação

Li N; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Zhang QY; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Zou JL; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Li ZW; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Tian TT; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Dong B; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Liu XJ; Central Laboratory, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Ge S; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Zhu Y; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Gao J; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Shen L; Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.

Oncotarget ; 7(4): 4817-28, 2016 Jan 26.

Article em En | MEDLINE | ID: mdl-26716895

Assuntos

Adenocarcinoma/patologia; Biomarcadores Tumorais/metabolismo; Subunidade alfa 2 de Fator de Ligação ao Core/metabolismo; Neoplasias Hepáticas/secundário; MicroRNAs/genética; Neoplasias Gástricas/patologia; Adenocarcinoma/genética; Adenocarcinoma/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Animais; Apoptose; Biomarcadores Tumorais/genética; Western Blotting; Ciclo Celular; Movimento Celular; Proliferação de Células; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Progressão da Doença; Feminino; Seguimentos; Regulação Neoplásica da Expressão Gênica; Humanos; Técnicas Imunoenzimáticas; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Pessoa de Meia-Idade; Invasividade Neoplásica; Estadiamento de Neoplasias; Prognóstico; RNA Mensageiro/genética; Reação em Cadeia da Polimerase em Tempo Real; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Neoplasias Gástricas/genética; Neoplasias Gástricas/metabolismo; Taxa de Sobrevida; Células Tumorais Cultivadas; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

RUNX1; gastric cancer; malignant progression; miR-215

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Adenocarcinoma / Biomarcadores Tumorais / MicroRNAs / Subunidade alfa 2 de Fator de Ligação ao Core / Neoplasias Hepáticas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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