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Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI.
Lee, Lawrence Soon-U; Seng, Kok-Yong; Wang, Ling-Zhi; Yong, Wei-Peng; Hee, Kim-Hor; Soh, Thomas I; Wong, Andrea; Cheong, Pei F; Soong, Richie; Sapari, Nur S; Soo, Ross; Fan, Lu; Lee, Soo-Chin; Goh, Boon C.
Afiliação
  • Lee LS; Department of Medicine, National University Health System, Singapore, Singapore.
  • Seng KY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Wang LZ; Department of Pharmacology, National University of Singapore, Singapore, Singapore.
  • Yong WP; Department of Pharmacology, National University of Singapore, Singapore, Singapore.
  • Hee KH; Cancer Science Institute, National University of Singapore, Singapore, Singapore.
  • Soh TI; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.
  • Wong A; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Cheong PF; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.
  • Soong R; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.
  • Sapari NS; Department of Haematology-Oncology, National University Health System, Singapore, Singapore.
  • Soo R; Department of Pharmacology, National University of Singapore, Singapore, Singapore.
  • Fan L; Department of Pharmacology, National University of Singapore, Singapore, Singapore.
  • Lee SC; Department of Medicine, National University Health System, Singapore, Singapore.
  • Goh BC; Department of Pharmacology, National University of Singapore, Singapore, Singapore.
PLoS One ; 11(1): e0147681, 2016.
Article em En | MEDLINE | ID: mdl-26808671

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Camptotecina / Glucuronosiltransferase / Raltegravir Potássico / Antineoplásicos Fitogênicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Singapura

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Camptotecina / Glucuronosiltransferase / Raltegravir Potássico / Antineoplásicos Fitogênicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Singapura