TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.

Bindesbøll, Christian; Tan, Susanna; Bott, Debbie; Cho, Tiffany; Tamblyn, Laura; MacPherson, Laura; Grønning-Wang, Line; Nebb, Hilde Irene; Matthews, Jason

Bindesbøll, Christian; Tan, Susanna; Bott, Debbie; Cho, Tiffany; Tamblyn, Laura; MacPherson, Laura; Grønning-Wang, Line; Nebb, Hilde Irene; Matthews, Jason.

Afiliação

Bindesbøll C; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 1046 Blindern, 0317 Oslo, Norway.
Tan S; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.
Bott D; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.
Cho T; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.
Tamblyn L; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.
MacPherson L; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.
Grønning-Wang L; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 1046 Blindern, 0317 Oslo, Norway.
Nebb HI; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 1046 Blindern, 0317 Oslo, Norway.
Matthews J; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 1046 Blindern, 0317 Oslo, Norway Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada jason.matthews@medisin.uio.no.

Biochem J ; 473(7): 899-910, 2016 Apr 01.

Article em En | MEDLINE | ID: mdl-26814197

Assuntos

ADP Ribose Transferases/metabolismo; Núcleo Celular/metabolismo; Receptores Nucleares Órfãos/metabolismo; Poli(ADP-Ribose) Polimerases/metabolismo; ADP Ribose Transferases/genética; Adenosina Difosfato Ribose/genética; Adenosina Difosfato Ribose/metabolismo; Animais; Células COS; Núcleo Celular/genética; Chlorocebus aethiops; Enzimas Reparadoras do DNA/genética; Enzimas Reparadoras do DNA/metabolismo; Células Hep G2; Humanos; Hidrolases/genética; Hidrolases/metabolismo; Receptores X do Fígado; Camundongos; Camundongos Knockout; Proteínas de Transporte de Nucleosídeos; Receptores Nucleares Órfãos/genética; Poli(ADP-Ribose) Polimerases/genética; Proteína de Ligação a Elemento Regulador de Esterol 1/genética; Proteína de Ligação a Elemento Regulador de Esterol 1/metabolismo

Palavras-chave

2; 3; 7; 8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase; ADP-ribosylation; gene regulation; liver X receptor; nuclear receptor; post-translational modification

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Celular / Poli(ADP-Ribose) Polimerases / ADP Ribose Transferases / Receptores Nucleares Órfãos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biochem J Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Noruega

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