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Design and discovery of 4-anilinoquinazoline-acylamino derivatives as EGFR and VEGFR-2 dual TK inhibitors.
Zhang, Hai-Qi; Gong, Fei-Hu; Li, Chuan-Gui; Zhang, Chi; Wang, Yan-Jie; Xu, Yun-Gen; Sun, Li-Ping.
Afiliação
  • Zhang HQ; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Gong FH; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Li CG; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Zhang C; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Wang YJ; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Xu YG; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
  • Sun LP; Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, PR China; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China. Electronic address: chslp@cpu.edu.cn.
Eur J Med Chem ; 109: 371-9, 2016 Feb 15.
Article em En | MEDLINE | ID: mdl-26826581
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Receptores ErbB / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Receptores ErbB / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2016 Tipo de documento: Article