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Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2.
Scheuer, Werner; Thomas, Markus; Hanke, Petra; Sam, Johannes; Osl, Franz; Weininger, Diana; Baehner, Monika; Seeber, Stefan; Kettenberger, Hubert; Schanzer, Jürgen; Brinkmann, Ulrich; Weidner, K Michael; Regula, Jörg; Klein, Christian.
Afiliação
  • Scheuer W; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Thomas M; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Hanke P; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Sam J; b Roche Innovation Center Zurich, Roche Pharma Research and Early Development , Wagistrasse 18, Schlieren , Switzerland.
  • Osl F; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Weininger D; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Baehner M; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Seeber S; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Kettenberger H; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Schanzer J; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Brinkmann U; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Weidner KM; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Regula J; a Roche Innovation Center Penzberg, Roche Pharma Research and Early Development , Nonnenwald 2, Penzberg , Germany.
  • Klein C; b Roche Innovation Center Zurich, Roche Pharma Research and Early Development , Wagistrasse 18, Schlieren , Switzerland.
MAbs ; 8(3): 562-73, 2016.
Article em En | MEDLINE | ID: mdl-26864324
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Angiopoietina-2 / Fator A de Crescimento do Endotélio Vascular / Anticorpos Antineoplásicos / Proteínas de Neoplasias / Neoplasias Experimentais / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Angiopoietina-2 / Fator A de Crescimento do Endotélio Vascular / Anticorpos Antineoplásicos / Proteínas de Neoplasias / Neoplasias Experimentais / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha