Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).

Qin, Jiayue; Wang, Zhizhi; Hoogeveen-Westerveld, Marianne; Shen, Guobo; Gong, Weimin; Nellist, Mark; Xu, Wenqing

Qin, Jiayue; Wang, Zhizhi; Hoogeveen-Westerveld, Marianne; Shen, Guobo; Gong, Weimin; Nellist, Mark; Xu, Wenqing.

Afiliação

Qin J; From the Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, the Department of Biological Structure, University of Washington, Seattle, Washington 98195, the University of Chinese Academy of Sciences, Beijing 100049, China.
Wang Z; the Department of Biological Structure, University of Washington, Seattle, Washington 98195.
Hoogeveen-Westerveld M; the Department of Clinical Genetics, Erasmus Medical Center, 3015CN Rotterdam, The Netherlands, and.
Shen G; the Department of Biological Structure, University of Washington, Seattle, Washington 98195.
Gong W; From the Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, the Hefei National Laboratory for Physical Science at Microscale, University of Science and Technology of China, Hefei 230026, China wgong@ibp.ac.cn.
Nellist M; the Department of Clinical Genetics, Erasmus Medical Center, 3015CN Rotterdam, The Netherlands, and m.nellist@erasmusmc.nl.
Xu W; From the Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China, the Department of Biological Structure, University of Washington, Seattle, Washington 98195, wxu@uw.edu.

J Biol Chem ; 291(16): 8591-601, 2016 Apr 15.

Article em En | MEDLINE | ID: mdl-26893383

Assuntos

Proteínas de Transporte/química; Proteínas Supressoras de Tumor/química; Proteínas de Transporte/genética; Proteínas de Transporte/metabolismo; Cristalografia por Raios X; Humanos; Peptídeos e Proteínas de Sinalização Intracelular; Estrutura Quaternária de Proteína; Estrutura Secundária de Proteína; Estrutura Terciária de Proteína; Proteína 1 do Complexo Esclerose Tuberosa; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo

Palavras-chave

TBC1D7; TSC1; crystal structure; isothermal titration calorimetry (ITC); mTOR complex (mTORC); protein complex; tuberous sclerosis complex (TSC)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Proteínas Supressoras de Tumor Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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