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Synthesis, biological evaluation and molecular docking studies of 2-piperazin-1-yl-quinazolines as platelet aggregation inhibitors and ligands of integrin αIIbß3.
Krysko, Andrei A; Kornylov, Alexander Yu; Polishchuk, Pavel G; Samoylenko, Georgiy V; Krysko, Olga L; Kabanova, Tatyana A; Kravtsov, Victor Ch; Kabanov, Vladimir M; Wicher, Barbara; Andronati, Sergei A.
Afiliação
  • Krysko AA; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine. Electronic address: peptides@physchem.od.ua.
  • Kornylov AY; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
  • Polishchuk PG; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital in Olomouc, Hnevotínská 1333/5, Olomouc 77900, Czech Republic.
  • Samoylenko GV; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
  • Krysko OL; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
  • Kabanova TA; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
  • Kravtsov VCh; Institute of Applied Physics, Academy of Sciences of Moldova, Academiei 5, Chisinau 2028, Republic of Moldova.
  • Kabanov VM; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
  • Wicher B; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.
  • Andronati SA; A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine, Lustdorfskaya doroga 86, Odessa 65080, Ukraine.
Bioorg Med Chem Lett ; 26(7): 1839-43, 2016 Apr 01.
Article em En | MEDLINE | ID: mdl-26912112

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Plaquetas / Inibidores da Agregação Plaquetária / Complexo Glicoproteico GPIIb-IIIa de Plaquetas Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Plaquetas / Inibidores da Agregação Plaquetária / Complexo Glicoproteico GPIIb-IIIa de Plaquetas Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article