Combining microCT-based characterization with empirical modelling as a robust screening approach for the design of optimized CaP-containing scaffolds for progenitor cell-mediated bone formation.

Kerckhofs, G; Chai, Y C; Luyten, F P; Geris, L

Kerckhofs, G; Chai, Y C; Luyten, F P; Geris, L.

Afiliação

Kerckhofs G; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium; Tissue Engineering Laboratory, Skeletal Biology and Engineering Research Center, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium
Chai YC; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium; Tissue Engineering Laboratory, Skeletal Biology and Engineering Research Center, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium
Luyten FP; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium; Tissue Engineering Laboratory, Skeletal Biology and Engineering Research Center, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium
Geris L; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Onderwijs en Navorsing 1, Herestraat 49 - PB813, B-3000 Leuven, Belgium; Biomechanics Research Unit, Université de Liège, Chemin des Chevreuils 1 - BAT 52/3, B-4000 Liège, Belgium; Division of Biomechanics and Engineering Design, KU Leu

Acta Biomater ; 35: 330-40, 2016 Apr 15.

Article em En | MEDLINE | ID: mdl-26925963

Assuntos

Fosfatos de Cálcio/farmacologia; Osteogênese/efeitos dos fármacos; Células-Tronco/citologia; Alicerces Teciduais/química; Microtomografia por Raio-X/métodos; Adolescente; Animais; Contagem de Células; Criança; Colágeno/análise; Feminino; Humanos; Masculino; Camundongos Nus; Porosidade

Palavras-chave

Empirical modelling; MicroCT characterization; Optimized calcium phosphate-based constructs; Robust screening

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Células-Tronco / Fosfatos de Cálcio / Alicerces Teciduais / Microtomografia por Raio-X Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adolescent / Animals / Child / Female / Humans / Male Idioma: En Revista: Acta Biomater Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

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