Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm.

Wakita, Daiko; Kurashima, Yosuke; Crother, Timothy R; Noval Rivas, Magali; Lee, Youngho; Chen, Shuang; Fury, Wen; Bai, Yu; Wagner, Shawn; Li, Debiao; Lehman, Thomas; Fishbein, Michael C; Hoffman, Hal M; Shah, Prediman K; Shimada, Kenichi; Arditi, Moshe

Wakita, Daiko; Kurashima, Yosuke; Crother, Timothy R; Noval Rivas, Magali; Lee, Youngho; Chen, Shuang; Fury, Wen; Bai, Yu; Wagner, Shawn; Li, Debiao; Lehman, Thomas; Fishbein, Michael C; Hoffman, Hal M; Shah, Prediman K; Shimada, Kenichi; Arditi, Moshe.

Afiliação

Wakita D; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Kurashima Y; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Crother TR; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Noval Rivas M; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Lee Y; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Chen S; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Fury W; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Bai Y; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Wagner S; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Li D; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Lehman T; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Fishbein MC; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Hoffman HM; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Shah PK; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Shimada K; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins
Arditi M; From the Division of Infectious Diseases and Immunology, Department of Biomedical Sciences and Pediatrics (D.W., T.R.C., M.N.R., Y.L., S.C., K.S., M.A.), Infectious and Immunologic Diseases Research Center, Department of Biomedical Sciences (T.R.C., S.C., K.S., M.A.), Biomedical Imaging Research Ins

Arterioscler Thromb Vasc Biol ; 36(5): 886-97, 2016 05.

Article em En | MEDLINE | ID: mdl-26941015

Assuntos

Aorta Abdominal/metabolismo; Aneurisma da Aorta Abdominal/metabolismo; Interleucina-1alfa/metabolismo; Interleucina-1beta/metabolismo; Síndrome de Linfonodos Mucocutâneos/complicações; Receptores Tipo I de Interleucina-1/metabolismo; Transdução de Sinais; Animais; Aorta Abdominal/efeitos dos fármacos; Aorta Abdominal/patologia; Aneurisma da Aorta Abdominal/genética; Aneurisma da Aorta Abdominal/patologia; Aneurisma da Aorta Abdominal/prevenção & controle; Aortite/genética; Aortite/metabolismo; Aortite/patologia; Caspase 1/deficiência; Caspase 1/genética; Proliferação de Células; Parede Celular; Dilatação Patológica; Modelos Animais de Doenças; Elastina/metabolismo; Feminino; Perfilação da Expressão Gênica; Genótipo; Humanos; Proteína Antagonista do Receptor de Interleucina 1/farmacologia; Interleucina-1alfa/deficiência; Interleucina-1alfa/genética; Interleucina-1beta/deficiência; Interleucina-1beta/genética; Lacticaseibacillus casei; Macrófagos/metabolismo; Macrófagos/patologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Síndrome de Linfonodos Mucocutâneos/induzido quimicamente; Síndrome de Linfonodos Mucocutâneos/tratamento farmacológico; Músculo Liso Vascular/metabolismo; Músculo Liso Vascular/patologia; Miócitos de Músculo Liso/metabolismo; Miócitos de Músculo Liso/patologia; Proteína 3 que Contém Domínio de Pirina da Família NLR/deficiência; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Fenótipo; Receptores Tipo I de Interleucina-1/deficiência; Receptores Tipo I de Interleucina-1/genética; Transdução de Sinais/efeitos dos fármacos; Fatores de Tempo

Palavras-chave

abdominal aortic aneurysm; aortitis; caspase-1; dilatation; vasculitis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aorta Abdominal / Transdução de Sinais / Aneurisma da Aorta Abdominal / Interleucina-1alfa / Interleucina-1beta / Receptores Tipo I de Interleucina-1 / Síndrome de Linfonodos Mucocutâneos Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Arterioscler Thromb Vasc Biol Assunto da revista: ANGIOLOGIA Ano de publicação: 2016 Tipo de documento: Article

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