Transmembrane signalling at the epidermal growth factor receptor.
Trends Pharmacol Sci
; 10(10): 411-4, 1989 Oct.
Article
em En
| MEDLINE
| ID: mdl-2694537
ABSTRACT
The EGF receptor, which is homologous to the v-erb-B oncogene product, has intrinsic tyrosine kinase activity, and mediates an increase in polyphosphoinositide turnover and [Ca2+]i. Recently, great progress has been made in understanding the mechanism of signal transduction at this receptor. Jacopo Meldolesi and colleagues discuss how this knowledge may lead to a better understanding of the control of cell proliferation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
/
Receptores ErbB
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Pharmacol Sci
Ano de publicação:
1989
Tipo de documento:
Article