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A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.
Yuan, Shuofeng; Chu, Hin; Singh, Kailash; Zhao, Hanjun; Zhang, Ke; Kao, Richard Y T; Chow, Billy K C; Zhou, Jie; Zheng, Bo-Jian.
Afiliação
  • Yuan S; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Chu H; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Singh K; School of Biological Sciences, The University of Hong Kong, Hong Kong SAR, China.
  • Zhao H; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Zhang K; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Kao RY; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Chow BK; School of Biological Sciences, The University of Hong Kong, Hong Kong SAR, China.
  • Zhou J; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
  • Zheng BJ; Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
Sci Rep ; 6: 22880, 2016 Mar 09.
Article em En | MEDLINE | ID: mdl-26956222

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Proteínas Virais / Replicação Viral / RNA Polimerase Dependente de RNA Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Proteínas Virais / Replicação Viral / RNA Polimerase Dependente de RNA Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China