Mesenchymal Stromal Cells as Cell-Based Therapeutics for Wound Healing.
Stem Cells Int
; 2016: 4157934, 2016.
Article
em En
| MEDLINE
| ID: mdl-26966438
ABSTRACT
Chronic wounds are a source of substantial morbidity for patients and are a major financial burden for the healthcare system. There are no current therapies that reliably improve nonhealing wounds or reverse pathological scarring. Mesenchymal stromal cells (MSCs) are a promising source of novel cell-based therapies due to the ease of their harvest and their integral role in the native wound repair process. Recent work has addressed the problems of loss of plasticity and off-target delivery through use of modern bioengineering techniques. Here we describe the applications of MSCs harvested from different sources to the wound healing process and recent advances in delivery of MSCs to targeted sites of injury.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Stem Cells Int
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos