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Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function.
Vijayvargia, Ravi; Epand, Raquel; Leitner, Alexander; Jung, Tae-Yang; Shin, Baehyun; Jung, Roy; Lloret, Alejandro; Singh Atwal, Randy; Lee, Hyeongseok; Lee, Jong-Min; Aebersold, Ruedi; Hebert, Hans; Song, Ji-Joon; Seong, Ihn Sik.
Afiliação
  • Vijayvargia R; Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States.
  • Epand R; Department of Neurology, Harvard Medical School, Boston, United States.
  • Leitner A; Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
  • Jung TY; Department of Biology, Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.
  • Shin B; Department of Biological Sciences, Cancer Metastasis Control Center, KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
  • Jung R; Department of Biosciences and Nutrition, Karolinska Institute, Solna, Sweden.
  • Lloret A; School of Technology and Health, KTH Royal Institute of Technology, Novum, Sweden.
  • Singh Atwal R; Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States.
  • Lee H; Department of Neurology, Harvard Medical School, Boston, United States.
  • Lee JM; Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States.
  • Aebersold R; Department of Neurology, Harvard Medical School, Boston, United States.
  • Hebert H; Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States.
  • Song JJ; Department of Neurology, Harvard Medical School, Boston, United States.
  • Seong IS; Center for Human Genetic Research, Massachusetts General Hospital, Boston, United States.
Elife ; 5: e11184, 2016 Mar 22.
Article em En | MEDLINE | ID: mdl-27003594
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Proteína Huntingtina Idioma: En Revista: Elife Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Proteína Huntingtina Idioma: En Revista: Elife Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos