The Structure of the Complex between Yeast Frataxin and Ferrochelatase: CHARACTERIZATION AND PRE-STEADY STATE REACTION OF FERROUS IRON DELIVERY AND HEME SYNTHESIS.

Söderberg, Christopher; Gillam, Mallory E; Ahlgren, Eva-Christina; Hunter, Gregory A; Gakh, Oleksandr; Isaya, Grazia; Ferreira, Gloria C; Al-Karadaghi, Salam

Söderberg, Christopher; Gillam, Mallory E; Ahlgren, Eva-Christina; Hunter, Gregory A; Gakh, Oleksandr; Isaya, Grazia; Ferreira, Gloria C; Al-Karadaghi, Salam.

Afiliação

Söderberg C; From the Center for Molecular Protein Science, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden.
Gillam ME; Department of Molecular Medicine, Morsani College of Medicine and.
Ahlgren EC; From the Center for Molecular Protein Science, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden.
Hunter GA; Department of Molecular Medicine, Morsani College of Medicine and.
Gakh O; the Departments of Pediatric and Adolescent Medicine and Biochemistry and Molecular Biology, Mayo Clinic, College of Medicine, Rochester, Minnesota 55905.
Isaya G; the Departments of Pediatric and Adolescent Medicine and Biochemistry and Molecular Biology, Mayo Clinic, College of Medicine, Rochester, Minnesota 55905.
Ferreira GC; Department of Molecular Medicine, Morsani College of Medicine and the Department of Chemistry, University of South Florida, Tampa, Florida 33612, and gferreir@health.usf.edu.
Al-Karadaghi S; From the Center for Molecular Protein Science, Department of Chemistry, Lund University, SE-221 00 Lund, Sweden, salam.al-karadaghi@biochemistry.lu.se.

J Biol Chem ; 291(22): 11887-98, 2016 May 27.

Article em En | MEDLINE | ID: mdl-27026703

Assuntos

Ferroquelatase/química; Ferroquelatase/metabolismo; Heme/biossíntese; Proteínas de Ligação ao Ferro/química; Proteínas de Ligação ao Ferro/metabolismo; Ferro/metabolismo; Saccharomyces cerevisiae/metabolismo; Cristalografia por Raios X; Cinética; Modelos Moleculares; Ligação Proteica; Conformação Proteica; Saccharomyces cerevisiae/crescimento & desenvolvimento; Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz; Frataxina

Palavras-chave

Friedreich ataxia; ataxia; ferrochelatase; frataxin; heme; iron chaperone; iron trafficking; iron-sulfur protein; mitochondria; protoporphyrin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas de Ligação ao Ferro / Ferroquelatase / Heme / Ferro Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suécia

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