Semantic memory assessment in 15 patients with amyotrophic lateral sclerosis.
Rev Neurol (Paris)
; 172(4-5): 307-12, 2016.
Article
em En
| MEDLINE
| ID: mdl-27157419
ABSTRACT
INTRODUCTION:
A total of 30 to 50% of amyotrophic lateral sclerosis patients suffer from cognitive disorders. The aim of the study is to characterize these disorders and to assess semantic memory in non-demented ALS patients. The secondary aim is to look for a link between disease type and neuropsychological characteristics.METHOD:
Patients were followed in an ALS center in Dijon. The following neuropsychological tests were used in this study Folstein test, BREF test, verbal fluency, Isaac test, GRESEM test and TOP 30 test.RESULTS:
Fifteen ALS patients were included. Nine of them (60%) were suffering from a semantic memory disorder. There was no correlation between ALS characteristics and the semantic memory disorder.DISCUSSION:
This is the first study to reveal a semantic memory disorder in ALS. This result accentuates the hypothesis that ALS and semantic dementia are two phenotypes of the same degenerative process linked to TDP 43 proteinopathy.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esclerose Lateral Amiotrófica
/
Memória
/
Transtornos da Memória
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Qualitative_research
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Rev Neurol (Paris)
Ano de publicação:
2016
Tipo de documento:
Article