Twin delivery after IVF-ET with variable dose letrozole-FSH protocol of lower estradiol in a patient previously treated for breast cancer: a case report.
Eur J Gynaecol Oncol
; 37(2): 278-81, 2016.
Article
em En
| MEDLINE
| ID: mdl-27172763
ABSTRACT
OBJECTIVE:
To present a case of twin pregnancy obtained by in vitro fertilization and embryo transfer (IVF-ET) with variable dose letrozole-FSH protocol of lower peak estradiol level, after treatment of carcinoma of the breast. MATERIALS ANDMETHODS:
A 34-year-old patient diagnosed with mucinous breast carcinoma undergoing assisted fertilization treatment after breast cancer operation and treatment including controlled ovarian stimulation (COS), oocyte retrieval, IVF, and embryo culture and transfer.RESULTS:
Four oocytes were obtained in three COS procedures in the three IVF cycle. All oocytes were fertilized. In the third cycle, two fresh embryos were transferred, and two healthy girls were born at 37 gestational weeks.CONCLUSION:
Variable dose letrozole-FSH protocol can maintain lower peak estradiol levels and reduce estrogen exposure after breast cancer operation and chemotherapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Indução da Ovulação
/
Triazóis
/
Neoplasias da Mama
/
Adenocarcinoma Mucinoso
/
Inibidores da Aromatase
/
Fármacos para a Fertilidade Feminina
/
Gravidez de Gêmeos
/
Infertilidade Feminina
/
Menotropinas
/
Nitrilas
Tipo de estudo:
Guideline
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Eur J Gynaecol Oncol
Ano de publicação:
2016
Tipo de documento:
Article