Mitochondria: Masters of Epigenetics.

Tatar, Marc; Sedivy, John M

Tatar, Marc; Sedivy, John M.

Afiliação

Tatar M; Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.
Sedivy JM; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA. Electronic address: john_sedivy@brown.edu.

Cell ; 165(5): 1052-1054, 2016 May 19.

Article em En | MEDLINE | ID: mdl-27203109

RESUMO

Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.

Assuntos

Proteínas de Caenorhabditis elegans/genética; Caenorhabditis elegans/metabolismo; Envelhecimento; Animais; Epigênese Genética; Humanos; Longevidade; Mitocôndrias/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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