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NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds.
Yu, Jun-Lan; Chen, Tian-Tian; Zhou, Chen; Lian, Fu-Lin; Tang, Xu-Long; Wen, Yi; Shen, Jing-Kang; Xu, Ye-Chun; Xiong, Bing; Zhang, Nai-Xia.
Afiliação
  • Yu JL; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
  • Chen TT; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhou C; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
  • Lian FL; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
  • Tang XL; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
  • Wen Y; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
  • Shen JK; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Xu YC; CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Xiong B; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang NX; Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; China & University of Chinese Academy of Sciences, Beijing 100049, China.
Acta Pharmacol Sin ; 37(7): 984-93, 2016 Jul.
Article em En | MEDLINE | ID: mdl-27238211
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China