Differential quantification of isobaric phosphopeptides using data-independent acquisition mass spectrometry.
Mol Biosyst
; 12(8): 2385-8, 2016 07 19.
Article
em En
| MEDLINE
| ID: mdl-27301801
ABSTRACT
Phosphorylation is a post-translational modification (PTM) fundamental for processes such as signal transduction and enzyme activity. We propose to apply data-independent acquisition (DIA) using mass spectrometry (MS) to determine unexplored phosphorylation events on isobarically modified peptides. Such peptides are commonly not quantitatively discriminated in phosphoproteomics due to their identical mass.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfopeptídeos
/
Espectrometria de Massas
Idioma:
En
Revista:
Mol Biosyst
Assunto da revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos