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Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
Concha, Nestor; Huang, Jianzhong; Bai, Xiaopeng; Benowitz, Andrew; Brady, Pat; Grady, LaShadric C; Kryn, Luz Helena; Holmes, David; Ingraham, Karen; Jin, Qi; Pothier Kaushansky, Laura; McCloskey, Lynn; Messer, Jeffrey A; O'Keefe, Heather; Patel, Amish; Satz, Alexander L; Sinnamon, Robert H; Schneck, Jessica; Skinner, Steve R; Summerfield, Jennifer; Taylor, Amy; Taylor, J David; Evindar, Ghotas; Stavenger, Robert A.
Afiliação
  • Concha N; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Huang J; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Bai X; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Benowitz A; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Brady P; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Grady LC; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Kryn LH; GlaxoSmithKline , 5 Moore Drive, Research Triangle Park, North Carolina 27009, United States.
  • Holmes D; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Ingraham K; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Jin Q; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Pothier Kaushansky L; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • McCloskey L; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Messer JA; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • O'Keefe H; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Patel A; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Satz AL; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Sinnamon RH; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Schneck J; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Skinner SR; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Summerfield J; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Taylor A; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Taylor JD; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • Evindar G; GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States.
  • Stavenger RA; GlaxoSmithKline , 1250 S. Collegeville Road, Collegeville, Pennsylvania 19426, United States.
J Med Chem ; 59(15): 7299-304, 2016 Aug 11.
Article em En | MEDLINE | ID: mdl-27379833
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Staphylococcus aureus / Alquil e Aril Transferases / Inibidores Enzimáticos / Descoberta de Drogas / Antibacterianos Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Staphylococcus aureus / Alquil e Aril Transferases / Inibidores Enzimáticos / Descoberta de Drogas / Antibacterianos Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos