Your browser doesn't support javascript.
loading
The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia.
Ralvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; Daali, Youssef; Rudolph, Uwe; Desmeules, Jules; Zeilhofer, Hanns Ulrich; Besson, Marie.
Afiliação
  • Ralvenius WT; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
  • Acuña MA; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
  • Benke D; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
  • Matthey A; Division of Clinical Pharmacology and Toxicology, Multidisciplinary Pain Center, Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, University of Geneva, 4 rue Gabrielle-Perret-Gentil, CH-1211 Geneva, Switzerland.
  • Daali Y; Division of Clinical Pharmacology and Toxicology, Multidisciplinary Pain Center, Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, University of Geneva, 4 rue Gabrielle-Perret-Gentil, CH-1211 Geneva, Switzerland.
  • Rudolph U; Laboratory of Genetic Neuropharmacology, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA.
  • Desmeules J; Division of Clinical Pharmacology and Toxicology, Multidisciplinary Pain Center, Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, University of Geneva, 4 rue Gabrielle-Perret-Gentil, CH-1211 Geneva, Switzerland.
  • Zeilhofer HU; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 10, CH-8093 Zürich, Switzerland; Drug Discovery Network Zurich (DDNZ), C
  • Besson M; Division of Clinical Pharmacology and Toxicology, Multidisciplinary Pain Center, Department of Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, University of Geneva, 4 rue Gabrielle-Perret-Gentil, CH-1211 Geneva, Switzerland.
Neuropharmacology ; 109: 366-375, 2016 10.
Article em En | MEDLINE | ID: mdl-27392635
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Receptores de GABA-A / Analgésicos não Narcóticos / Hiperalgesia Limite: Animals / Female / Humans / Male Idioma: En Revista: Neuropharmacology Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Receptores de GABA-A / Analgésicos não Narcóticos / Hiperalgesia Limite: Animals / Female / Humans / Male Idioma: En Revista: Neuropharmacology Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça