Does cognitive decline decrease health utility value in older adult patients with cancer?
Psychogeriatrics
; 17(3): 149-154, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-27411897
ABSTRACT
AIM:
Cognitive decline is common among older adults with cancer. The present study aimed to investigate the impact of cognitive decline on health utility value in older adults suffering from cancer.METHODS:
Consecutive patients aged 65 years or older with a primary diagnosis of malignant lymphoma or multiple myeloma were recruited. Patients were asked to complete the EuroQoL-5 (EQ-5D) scale to measure health utility and the Mini-Mental State Examination to assess cognitive decline. The potential impact of cognitive decline was investigated with univariate analysis. A multivariate regression analysis was conducted to control for potential confounding factors.RESULTS:
Complete data were obtained from 87 patients, 29% of whom had cognitive decline. The mean ± SE EQ-5D score for patients with cognitive decline was significantly lower than that for those without cognitive decline (0.67 ± 0.04 vs 0.79 ± 0.03, t = 2.38, P = 0.02). However, multiple regression analysis showed that cognitive decline was not significantly associated with EQ-5D scores. Female sex and lower performance scores (worse physical condition) were significantly associated with EQ-5D scores.CONCLUSIONS:
Cognitive decline may be involved in decreased health utility value in older adult patients with cancer. However, this effect does not seem to be independent, and the patient's physical condition may be a relevant confounding factor.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Nível de Saúde
/
Indicadores Básicos de Saúde
/
Disfunção Cognitiva
/
Linfoma
/
Mieloma Múltiplo
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Psychogeriatrics
Assunto da revista:
GERIATRIA
/
PSICOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Japão