The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas.

Nettersheim, Daniel; Arndt, Isabell; Sharma, Rakesh; Riesenberg, Stefanie; Jostes, Sina; Schneider, Simon; Hölzel, Michael; Kristiansen, Glen; Schorle, Hubert

Nettersheim, Daniel; Arndt, Isabell; Sharma, Rakesh; Riesenberg, Stefanie; Jostes, Sina; Schneider, Simon; Hölzel, Michael; Kristiansen, Glen; Schorle, Hubert.

Afiliação

Nettersheim D; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Arndt I; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Sharma R; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Riesenberg S; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn Medical School, 53127 Bonn, Germany.
Jostes S; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Schneider S; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Hölzel M; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn Medical School, 53127 Bonn, Germany.
Kristiansen G; Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.
Schorle H; Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School, 53127 Bonn, Germany.

Br J Cancer ; 115(4): 454-64, 2016 08 09.

Article em En | MEDLINE | ID: mdl-27441500

Assuntos

Antígenos de Neoplasias/genética; Diferenciação Celular/genética; Células Germinativas/metabolismo; RNA Mensageiro/metabolismo; Seminoma/genética; Neoplasias Testiculares/genética; Testículo/metabolismo; Antígenos de Neoplasias/metabolismo; Western Blotting; Linhagem Celular Tumoral; Células Cultivadas; Técnicas de Silenciamento de Genes; Humanos; Imuno-Histoquímica; Masculino; RNA Interferente Pequeno; Reação em Cadeia da Polimerase em Tempo Real; Seminoma/metabolismo; Neoplasias Testiculares/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Testiculares / Testículo / RNA Mensageiro / Diferenciação Celular / Seminoma / Células Germinativas / Antígenos de Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: Br J Cancer Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha

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