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Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells.
Liao, Yi; Niu, Xiaojia; Chen, Bailing; Edwards, Holly; Xu, Liping; Xie, Chengzhi; Lin, Hai; Polin, Lisa; Taub, Jeffrey W; Ge, Yubin; Qin, Zhihui.
Afiliação
  • Liao Y; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University , Detroit, Michigan 48201, United States.
  • Niu X; Department of Pediatrics, Wayne State University School of Medicine , Detroit, Michigan 48201, United States.
  • Chen B; School of Life Sciences, Jilin University , Changchun 130012, P.R. China.
  • Edwards H; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University , Detroit, Michigan 48201, United States.
  • Xu L; Department of Oncology, Wayne State University School of Medicine , Detroit, Michigan 48201, United States.
  • Xie C; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute , Detroit, Michigan 48201, United States.
  • Lin H; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University , Detroit, Michigan 48201, United States.
  • Polin L; Department of Oncology, Wayne State University School of Medicine , Detroit, Michigan 48201, United States.
  • Taub JW; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute , Detroit, Michigan 48201, United States.
  • Ge Y; Department of Hematology and Oncology, The First Hospital of Jilin University , Changchun, P.R. China.
  • Qin Z; Department of Oncology, Wayne State University School of Medicine , Detroit, Michigan 48201, United States.
J Med Chem ; 59(17): 7974-90, 2016 09 08.
Article em En | MEDLINE | ID: mdl-27505848
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dioxolanos / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos / Antineoplásicos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dioxolanos / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos / Antineoplásicos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos