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Human CD40 ligand deficiency dysregulates the macrophage transcriptome causing functional defects that are improved by exogenous IFN-γ.
Cabral-Marques, Otavio; Ramos, Rodrigo Nalio; Schimke, Lena F; Khan, Taj Ali; Amaral, Eduardo Pinheiro; Barbosa Bomfim, Caio César; Junior, Osvaldo Reis; França, Tabata Takahashi; Arslanian, Christina; Carola Correia Lima, Joanna Darck; Weber, Cristina Worm; Ferreira, Janaíra Fernandes; Tavares, Fabiola Scancetti; Sun, Jing; D'Imperio Lima, Maria Regina; Seelaender, Marília; Garcia Calich, Vera Lucia; Marzagão Barbuto, José Alexandre; Costa-Carvalho, Beatriz Tavares; Riemekasten, Gabriela; Seminario, Gisela; Bezrodnik, Liliana; Notarangelo, Luigi; Torgerson, Troy R; Ochs, Hans D; Condino-Neto, Antonio.
Afiliação
  • Cabral-Marques O; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil; Department of Rheumatology, University Lübeck, Lübeck, Germany.
  • Ramos RN; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Schimke LF; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil; Department of Rheumatology, University Lübeck, Lübeck, Germany.
  • Khan TA; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil; Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan.
  • Amaral EP; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Barbosa Bomfim CC; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Junior OR; Central Laboratory of High Performance Technologies (LaCTAD), State University of Campinas, São Paulo, Brazil.
  • França TT; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Arslanian C; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Carola Correia Lima JD; Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Weber CW; Pediatric Allergy & Immunology Clinic, Caxias do Sul, Brazil.
  • Ferreira JF; Albert Sabin Hospital, Fortaleza, Brazil.
  • Tavares FS; Pediatric Immunology Clínic, Unit of Pediatrics, Hopital de Base do Distrito Federal Brasilia, Brasilia, Brazil.
  • Sun J; University of Cincinnati College of Medicine, Cincinnati, Ohio.
  • D'Imperio Lima MR; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Seelaender M; Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Garcia Calich VL; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Marzagão Barbuto JA; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil; Cell and Molecular Therapy Center, NETCEM, University of São Paulo, São Paulo, Brazil.
  • Costa-Carvalho BT; Division of Allergy-Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
  • Riemekasten G; Department of Rheumatology, University Lübeck, Lübeck, Germany.
  • Seminario G; Dr Ricardo Gutierrez Children's Hospital, Immunology, Buenos Aires, Argentina.
  • Bezrodnik L; Dr Ricardo Gutierrez Children's Hospital, Immunology, Buenos Aires, Argentina.
  • Notarangelo L; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
  • Torgerson TR; Department of Pediatrics, University of Washington School of Medicine, and Seattle Children's Research Institute, Seattle, Wash.
  • Ochs HD; Department of Pediatrics, University of Washington School of Medicine, and Seattle Children's Research Institute, Seattle, Wash.
  • Condino-Neto A; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address: condino@icb.usp.br.
J Allergy Clin Immunol ; 139(3): 900-912.e7, 2017 Mar.
Article em En | MEDLINE | ID: mdl-27554817
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon gama / Ligante de CD40 / Síndromes de Imunodeficiência / Macrófagos Limite: Adolescent / Adult / Child / Child, preschool / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon gama / Ligante de CD40 / Síndromes de Imunodeficiência / Macrófagos Limite: Adolescent / Adult / Child / Child, preschool / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha