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Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation.
Grasso, Michael; Estrada, Michelle A; Ventocilla, Christian; Samanta, Minu; Maksimoska, Jasna; Villanueva, Jessie; Winkler, Jeffrey D; Marmorstein, Ronen.
Afiliação
  • Grasso M; Department of Biochemistry and Biophysics and the Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania , 421 Curie Blvd., Philadelphia, Pennsylvania 19104, United States.
  • Estrada MA; Department of Chemistry, University of Pennsylvania , 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States.
  • Ventocilla C; Department of Chemistry, University of Pennsylvania , 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States.
  • Samanta M; Department of Chemistry, University of Pennsylvania , 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States.
  • Maksimoska J; Wistar Institute, Philadelphia , 3601 Spruce Street, Philadelphia, Pennsylvania 19104, United States.
  • Villanueva J; Department of Chemistry, University of Pennsylvania , 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States.
  • Winkler JD; Wistar Institute, Philadelphia , 3601 Spruce Street, Philadelphia, Pennsylvania 19104, United States.
  • Marmorstein R; Department of Chemistry, University of Pennsylvania , 231 S. 34th Street, Philadelphia, Pennsylvania 19104, United States.
ACS Chem Biol ; 11(10): 2876-2888, 2016 10 21.
Article em En | MEDLINE | ID: mdl-27571413
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Proteínas Proto-Oncogênicas B-raf / Indóis Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Proteínas Proto-Oncogênicas B-raf / Indóis Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos