SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation.

Xu, Shuang-Nian; Wang, Tian-Shi; Li, Xi; Wang, Yi-Ping

Xu, Shuang-Nian; Wang, Tian-Shi; Li, Xi; Wang, Yi-Ping.

Afiliação

Xu SN; Department of Haematology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Wang TS; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumour Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, 280 Chongqing South Rd., Shanghai 200025, China.
Li X; Department of Haematology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Wang YP; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumour Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, 280 Chongqing South Rd., Shanghai 200025, China.

Sci Rep ; 6: 32734, 2016 09 02.

Article em En | MEDLINE | ID: mdl-27586085

Assuntos

Proliferação de Células; Glucosefosfato Desidrogenase/metabolismo; Leucemia Mieloide Aguda/patologia; NADP/análise; Sirtuína 2/metabolismo; Linhagem Celular Tumoral; Técnicas de Silenciamento de Genes; Glucosefosfato Desidrogenase/genética; Humanos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Proliferação de Células / Sirtuína 2 / Glucosefosfato Desidrogenase / NADP Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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