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The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress.
Testai, Lara; Marino, Alice; Piano, Ilaria; Brancaleone, Vincenzo; Tomita, Kengo; Di Cesare Mannelli, Lorenzo; Martelli, Alma; Citi, Valentina; Breschi, Maria C; Levi, Roberto; Gargini, Claudia; Bucci, Mariarosaria; Cirino, Giuseppe; Ghelardini, Carla; Calderone, Vincenzo.
Afiliação
  • Testai L; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Marino A; Department of Pharmacology, Weill Cornell Medicine, New York, USA.
  • Piano I; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Brancaleone V; Department of Science, University of Basilicata, Potenza, Italy.
  • Tomita K; Department of Pharmacology, Weill Cornell Medicine, New York, USA.
  • Di Cesare Mannelli L; Department of Neuroscience, Psychology, Drug Research and Child Health (Neurofarba), University of Florence, Florence, Italy.
  • Martelli A; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Citi V; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Breschi MC; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Levi R; Department of Pharmacology, Weill Cornell Medicine, New York, USA.
  • Gargini C; Department of Pharmacy, University of Pisa, Pisa, Italy.
  • Bucci M; Department of Pharmacy, University of Naples Federico II, Naples, Italy.
  • Cirino G; Department of Pharmacy, University of Naples Federico II, Naples, Italy.
  • Ghelardini C; Department of Neuroscience, Psychology, Drug Research and Child Health (Neurofarba), University of Florence, Florence, Italy.
  • Calderone V; Department of Pharmacy, University of Pisa, Pisa, Italy. Electronic address: calderone@farm.unipi.it.
Pharmacol Res ; 113(Pt A): 290-299, 2016 11.
Article em En | MEDLINE | ID: mdl-27616550
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiotônicos / Traumatismo por Reperfusão Miocárdica / Canais de Potássio / Isotiocianatos / Estresse Oxidativo / Sulfeto de Hidrogênio Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiotônicos / Traumatismo por Reperfusão Miocárdica / Canais de Potássio / Isotiocianatos / Estresse Oxidativo / Sulfeto de Hidrogênio Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Itália