4,5-Disubstituted 6-Aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles Are Broad-Spectrum Serine ß-Lactamase Inhibitors.

McKinney, David C; Zhou, Fei; Eyermann, Charles J; Ferguson, Andrew D; Prince, D Bryan; Breen, John; Giacobbe, Robert A; Lahiri, Sushmita; Verheijen, Jeroen C

McKinney, David C; Zhou, Fei; Eyermann, Charles J; Ferguson, Andrew D; Prince, D Bryan; Breen, John; Giacobbe, Robert A; Lahiri, Sushmita; Verheijen, Jeroen C.

Afiliação

McKinney DC; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.
Zhou F; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.
Eyermann CJ; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.
Giacobbe RA; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.
Lahiri S; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.
Verheijen JC; Infection Innovative Medicines, AstraZeneca R&D Boston , 35 Gatehouse Drive, Waltham Massachusetts 02451, United States.

ACS Infect Dis ; 1(7): 310-6, 2015 Jul 10.

Article em En | MEDLINE | ID: mdl-27622821

Palavras-chave

Gram-negative infections; oxaboroles; structure-guided design; ß-lactamase inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Infect Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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