Hypophyseal metastases: A report of three cases and literature review.
Neurol Neurochir Pol
; 50(6): 511-516, 2016.
Article
em En
| MEDLINE
| ID: mdl-27633123
ABSTRACT
Metastatic tumours to the pituitary gland are rare. The most frequent are metastases from breast and lung. We describe three patients with metastatic tumours (I) a 54-year-old patient with metastatic renal clear-cell carcinoma and consequent disturbances in visual acuity, cranial nerve paresis and panhypopituitarism, (II) a 60-year-old patient with a diffuse large B-cell lymphoma with panhypopituitarism and diabetes insipidus and (III) a 57-year-old patient with metastasis of breast cancer and panhypopituitarism, visual impairment and cranial nerve paresis. A transnasal endoscopic biopsy and resection of the tumour was performed in all patients, followed by the oncological treatment. Despite the rarity of the disease, it is important to suspect a metastatic pituitary tumour especially in the case of diabetes insipidus, ophthalmoplegia, rapid course of the disease and headaches. In 20-30% of patients, a metastasis to the pituitary is the first manifestation of a tumour of unknown origin. Surgical and adjuvant therapy may improve the quality of life. The survival is not affected, however, and the prognosis of the disease is usually poor.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Hipofisárias
/
Neoplasias da Mama
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Carcinoma
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Carcinoma de Células Renais
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Linfoma Difuso de Grandes Células B
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Neoplasias das Glândulas Suprarrenais
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Neoplasias Renais
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Neurol Neurochir Pol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Eslovênia