Adipose-derived stem cell exosomes alleviate pathology of amyotrophic lateral sclerosis in vitro.

Lee, Mijung; Ban, Jae-Jun; Kim, Ki Yoon; Jeon, Gye Sun; Im, Wooseok; Sung, Jung-Joon; Kim, Manho

Adipose-derived stem cell exosomes alleviate pathology of amyotrophic lateral sclerosis in vitro.

Lee, Mijung; Ban, Jae-Jun; Kim, Ki Yoon; Jeon, Gye Sun; Im, Wooseok; Sung, Jung-Joon; Kim, Manho.

Afiliação

Lee M; Department of Neurology, Seoul National University Hospital, Seoul, South Korea.
Ban JJ; Department of Neurology, Seoul National University Hospital, Seoul, South Korea.
Kim KY; Department of Neurology, Seoul National University Hospital, Seoul, South Korea.
Jeon GS; Department of Neurology, Seoul National University Hospital, Seoul, South Korea.
Im W; Department of Neurology, Seoul National University Hospital, Seoul, South Korea; Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea. Electronic address: imwooseok@gmail.com.
Sung JJ; Department of Neurology, Seoul National University Hospital, Seoul, South Korea.
Kim M; Department of Neurology, Seoul National University Hospital, Seoul, South Korea; Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul, South Korea. Electronic address: kimmanho@snu.ac.kr.

Biochem Biophys Res Commun ; 479(3): 434-439, 2016 Oct 21.

Article em En | MEDLINE | ID: mdl-27641665

Assuntos

Adipócitos/citologia; Esclerose Lateral Amiotrófica/metabolismo; Esclerose Lateral Amiotrófica/terapia; Exossomos/metabolismo; Células-Tronco/citologia; Tecido Adiposo/citologia; Animais; Células Cultivadas; Citoplasma/metabolismo; Modelos Animais de Doenças; Humanos; Camundongos; Camundongos Transgênicos; Mitocôndrias/metabolismo; Neurônios Motores/metabolismo; Neurônios/metabolismo; Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo/metabolismo; Fenótipo; Superóxido Dismutase-1/metabolismo

Palavras-chave

ALS; Adipose-derived stem cell; Exosome; Neuronal stem cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco / Adipócitos / Exossomos / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Coréia do Sul

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