Glyoxalase 2 Is Involved in Human Prostate Cancer Progression as Part of a Mechanism Driven By PTEN/PI3K/AKT/mTOR Signaling With Involvement of PKM2 and ER&#945;.

Talesa, Vincenzo N; Ferri, Ivana; Bellezza, Guido; Love, Harold D; Sidoni, Angelo; Antognelli, Cinzia

Glyoxalase 2 Is Involved in Human Prostate Cancer Progression as Part of a Mechanism Driven By PTEN/PI3K/AKT/mTOR Signaling With Involvement of PKM2 and ERα.

Talesa, Vincenzo N; Ferri, Ivana; Bellezza, Guido; Love, Harold D; Sidoni, Angelo; Antognelli, Cinzia.

Afiliação

Talesa VN; Division of Biosciences and Medical Embryology, Department of Experimental Medicine, School of Medicine and Surgery, University of Perugia, Perugia, Italy.
Ferri I; Division of Anatomic Pathology and Histology, Department of Experimental Medicine, School of Medicine and Surgery, University of Perugia, Perugia, Italy.
Bellezza G; Division of Anatomic Pathology and Histology, Department of Experimental Medicine, School of Medicine and Surgery, University of Perugia, Perugia, Italy.
Love HD; Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Sidoni A; Division of Anatomic Pathology and Histology, Department of Experimental Medicine, School of Medicine and Surgery, University of Perugia, Perugia, Italy.
Antognelli C; Division of Biosciences and Medical Embryology, Department of Experimental Medicine, School of Medicine and Surgery, University of Perugia, Perugia, Italy.

Prostate ; 77(2): 196-210, 2017 02.

Article em En | MEDLINE | ID: mdl-27696457

Assuntos

Proteínas de Transporte/metabolismo; Receptor alfa de Estrogênio/metabolismo; Lactoilglutationa Liase/metabolismo; Proteínas de Membrana/metabolismo; Neoplasias da Próstata/metabolismo; Neoplasias da Próstata/patologia; Tioléster Hidrolases/metabolismo; Hormônios Tireóideos/metabolismo; Biomarcadores Tumorais/metabolismo; Linhagem Celular Transformada; Progressão da Doença; Humanos; Masculino; PTEN Fosfo-Hidrolase/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais/fisiologia; Serina-Treonina Quinases TOR/metabolismo; Proteínas de Ligação a Hormônio da Tireoide

Palavras-chave

ER-α; PKM2; PTEN; glyoxalases; prostate cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Tioléster Hidrolases / Hormônios Tireóideos / Proteínas de Transporte / Receptor alfa de Estrogênio / Lactoilglutationa Liase / Proteínas de Membrana Limite: Humans / Male Idioma: En Revista: Prostate Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália

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