Impact of intravesical onabotulinumtoxinA on sexual function in women with OAB.
Neurourol Urodyn
; 36(6): 1564-1569, 2017 Aug.
Article
em En
| MEDLINE
| ID: mdl-27701762
ABSTRACT
AIMS:
Urgency urinary incontinence (UUI), and the symptoms of overactive bladder (OAB) have a negative impact on female sexual function. The aim of this study was to investigate the effect of intravesical onabotulinumtoxinA (Botox) injection on sexual function in women with OAB, using the multi domain Female Sexual Function Index (FSFI) questionnaire.METHODS:
Sixty-eight sexually active women with idiopathic OAB with at least one episode of UUI and ≥8 micturitions per 24 h were recruited. Patients completed the FSFI questionnaire before and 12 weeks after treatment with intravesical onabotulinumtoxinA injections. Baseline scores were compared with a control group of age-matched healthy women.RESULTS:
Fifty-six women completed the study. At baseline OAB patients reported decreased quality of sexual function in all domains measured with FSFI, in comparison to healthy women (median 21.8 vs. 26.3, P < 0.001). Over 90% of participants reported clinically relevant improvements in sexual function, with statistically significant changes in mean scores in all six domains.CONCLUSIONS:
Intravesical Botox injections provide improvement in sexual function in women with OAB. Neurourol. Urodynam. 9999XX-XX, 2016. © 2016 Wiley Periodicals, Inc.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disfunções Sexuais Fisiológicas
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Toxinas Botulínicas Tipo A
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Bexiga Urinária Hiperativa
Limite:
Adult
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Neurourol Urodyn
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Polônia