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Building the SeqChromMM Markov property atlas of the human genome by analyzing the 200-bp units of the 15 different chromatin regions of ENCODE.
Lee, K-E; Park, H-S.
Afiliação
  • Lee KE; Bioinformatics Laboratory, Engineering School, Ewha Womans University, Seoul, Korea.
  • Park HS; Bioinformatics Laboratory, Engineering School, Ewha Womans University, Seoul, Korea neo@ewha.ac.kr.
Genet Mol Res ; 15(3)2016 Aug 30.
Article em En | MEDLINE | ID: mdl-27706663
We analyzed the publicly available ChromHMM BED files of the ENCODE project and tested the Markov properties of the different chromatin states in the human genome. Nucleotide frequency profiles of regional chromatin segmentations were analyzed, and Markov chains were built to detect Markov properties in the chromatin states of different ChromHMM regions. By estimating the transition probabilities of 200-base pair nucleotide sequences of the human genome, we constructed a nucleotide-sequence-based Markovian chromatin map called SeqChromMM.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Cromossomos Humanos Tipo de estudo: Health_economic_evaluation Limite: Humans Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Cromossomos Humanos Tipo de estudo: Health_economic_evaluation Limite: Humans Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2016 Tipo de documento: Article