SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes.

Brannan, Kristopher W; Jin, Wenhao; Huelga, Stephanie C; Banks, Charles A S; Gilmore, Joshua M; Florens, Laurence; Washburn, Michael P; Van Nostrand, Eric L; Pratt, Gabriel A; Schwinn, Marie K; Daniels, Danette L; Yeo, Gene W

Brannan, Kristopher W; Jin, Wenhao; Huelga, Stephanie C; Banks, Charles A S; Gilmore, Joshua M; Florens, Laurence; Washburn, Michael P; Van Nostrand, Eric L; Pratt, Gabriel A; Schwinn, Marie K; Daniels, Danette L; Yeo, Gene W.

Afiliação

Brannan KW; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Jin W; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore, Singapore.
Huelga SC; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Banks CA; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Gilmore JM; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Florens L; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Washburn MP; Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
Van Nostrand EL; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Pratt GA; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Schwinn MK; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA.
Daniels DL; Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711, USA.
Yeo GW; Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore, Singapore; Molecular Engin

Mol Cell ; 64(2): 282-293, 2016 10 20.

Article em En | MEDLINE | ID: mdl-27720645

Assuntos

Algoritmos; Anotação de Sequência Molecular; Proteínas de Ligação a RNA/química; Proteínas de Ligação a RNA/classificação; RNA/química; Animais; Sítios de Ligação; Núcleo Celular/química; Núcleo Celular/metabolismo; Citoplasma/química; Citoplasma/metabolismo; Drosophila melanogaster/genética; Drosophila melanogaster/metabolismo; Expressão Gênica; Ontologia Genética; Células HEK293; Humanos; Motivos de Nucleotídeos; Ligação Proteica; Domínios e Motivos de Interação entre Proteínas; RNA/genética; RNA/metabolismo; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo; Saccharomyces cerevisiae/genética; Saccharomyces cerevisiae/metabolismo; Software; Dedos de Zinco

Palavras-chave

RNA-binding proteins; machine-learning; protein-protein interaction networks; support vector machine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Algoritmos / RNA / Proteínas de Ligação a RNA / Anotação de Sequência Molecular Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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