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Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Yu, Shan; Pearson, Aaron D; Lim, Reyna Kv; Rodgers, David T; Li, Sijia; Parker, Holly B; Weglarz, Meredith; Hampton, Eric N; Bollong, Michael J; Shen, Jiayin; Zambaldo, Claudio; Wang, Danling; Woods, Ashley K; Wright, Timothy M; Schultz, Peter G; Kazane, Stephanie A; Young, Travis S; Tremblay, Matthew S.
Afiliação
  • Yu S; California Institute for Biomedical Research, La Jolla, California, USA.
  • Pearson AD; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Lim RK; California Institute for Biomedical Research, La Jolla, California, USA.
  • Rodgers DT; California Institute for Biomedical Research, La Jolla, California, USA.
  • Li S; California Institute for Biomedical Research, La Jolla, California, USA.
  • Parker HB; California Institute for Biomedical Research, La Jolla, California, USA.
  • Weglarz M; California Institute for Biomedical Research, La Jolla, California, USA.
  • Hampton EN; California Institute for Biomedical Research, La Jolla, California, USA.
  • Bollong MJ; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Shen J; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Zambaldo C; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Wang D; California Institute for Biomedical Research, La Jolla, California, USA.
  • Woods AK; California Institute for Biomedical Research, La Jolla, California, USA.
  • Wright TM; California Institute for Biomedical Research, La Jolla, California, USA.
  • Schultz PG; California Institute for Biomedical Research, La Jolla, California, USA.
  • Kazane SA; Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Young TS; California Institute for Biomedical Research, La Jolla, California, USA.
  • Tremblay MS; California Institute for Biomedical Research, La Jolla, California, USA.
Mol Ther ; 24(12): 2078-2089, 2016 Dec.
Article em En | MEDLINE | ID: mdl-27731313
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonas / Imunoconjugados / Antígenos CD11 / Inibidores da Fosfodiesterase 4 / Aminoquinolinas / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonas / Imunoconjugados / Antígenos CD11 / Inibidores da Fosfodiesterase 4 / Aminoquinolinas / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos