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The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models.
Zhang, Sen; Anjum, Rana; Squillace, Rachel; Nadworny, Sara; Zhou, Tianjun; Keats, Jeff; Ning, Yaoyu; Wardwell, Scott D; Miller, David; Song, Youngchul; Eichinger, Lindsey; Moran, Lauren; Huang, Wei-Sheng; Liu, Shuangying; Zou, Dong; Wang, Yihan; Mohemmad, Qurish; Jang, Hyun Gyung; Ye, Emily; Narasimhan, Narayana; Wang, Frank; Miret, Juan; Zhu, Xiaotian; Clackson, Tim; Dalgarno, David; Shakespeare, William C; Rivera, Victor M.
Afiliação
  • Zhang S; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Anjum R; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Squillace R; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Nadworny S; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Zhou T; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Keats J; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Ning Y; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Wardwell SD; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Miller D; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Song Y; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Eichinger L; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Moran L; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Huang WS; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Liu S; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Zou D; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Wang Y; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Mohemmad Q; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Jang HG; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Ye E; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Narasimhan N; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Wang F; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Miret J; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Zhu X; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Clackson T; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Dalgarno D; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Shakespeare WC; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts.
  • Rivera VM; ARIAD Pharmaceuticals, Inc, Cambridge, Massachusetts. victor.rivera@ariad.com.
Clin Cancer Res ; 22(22): 5527-5538, 2016 Nov 15.
Article em En | MEDLINE | ID: mdl-27780853
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organofosforados / Pirimidinas / Receptores Proteína Tirosina Quinases / Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organofosforados / Pirimidinas / Receptores Proteína Tirosina Quinases / Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article