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Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance.
Raaijmakers, Marieke I G; Widmer, Daniel S; Narechania, Apurva; Eichhoff, Ossia; Freiberger, Sandra N; Wenzina, Judith; Cheng, Phil F; Mihic-Probst, Daniela; Desalle, Rob; Dummer, Reinhard; Levesque, Mitchell P.
Afiliação
  • Raaijmakers MI; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Widmer DS; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Narechania A; American Museum of Natural History, New York, New York, USA.
  • Eichhoff O; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Freiberger SN; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Wenzina J; Department of Dermatology, Skin and Endothelium Research Division, Medical University of Vienna, Austria.
  • Cheng PF; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Mihic-Probst D; Department of Dermatology, Skin and Endothelium Research Division, Medical University of Vienna, Austria.
  • Desalle R; Department of Dermatology, University of Zurich, University Hospital Zürich, Switzerland.
  • Dummer R; Department of Pathology, University of Zurich, University Hospital Zürich, Switzerland.
  • Levesque MP; American Museum of Natural History, New York, New York, USA.
Oncotarget ; 7(47): 77163-77174, 2016 11 22.
Article em En | MEDLINE | ID: mdl-27791198
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas B-raf / GTP Fosfo-Hidrolases / Melanoma / Proteínas de Membrana / Mutação Limite: Female / Humans / Male Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas B-raf / GTP Fosfo-Hidrolases / Melanoma / Proteínas de Membrana / Mutação Limite: Female / Humans / Male Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça