Patterning Electrospun Nanofibers via Agarose Hydrogel Stamps to Spatially Coordinate Cell Orientation in Microfluidic Device.

Hu, Tao; Li, Qingtao; Dong, Hua; Xiao, Wenwu; Li, Ling; Cao, Xiaodong

Hu, Tao; Li, Qingtao; Dong, Hua; Xiao, Wenwu; Li, Ling; Cao, Xiaodong.

Afiliação

Hu T; Department of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, China.
Li Q; National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, 510641, China.
Dong H; Guangdong Province Key Laboratory of Biomedical Engineering, South China University of Technology, Guangzhou, 510641, China.
Xiao W; National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, 510641, China.
Li L; School of Medicine, South China University of Technology, Guangzhou, 510006, China.
Cao X; Department of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, China.

Small ; 13(3)2017 Jan.

Article em En | MEDLINE | ID: mdl-27792275

ABSTRACT

ABSTRACT

A straightforward, inexpensive, and reliable approach to pattern electrospun nanofibers via solvent-containing agarose hydrogel stamps is reported. Complex hierarchical microstructures can be further constructed via appropriate multistep permutation of microcontact patterning and electrospinning. As a proof-of-concept application, the patterned electrospun nanofibers are employed to spatially coordinate cell orientation in microfluidic devices.

Assuntos

Hidrogel de Polietilenoglicol-Dimetacrilato/química; Dispositivos Lab-On-A-Chip; Células-Tronco Mesenquimais/citologia; Nanofibras/química; Nanotecnologia/instrumentação; Nanotecnologia/métodos; Sefarose/química; Animais; Humanos; Nanofibras/ultraestrutura; Poliésteres/química; Trifluoretanol/química

Palavras-chave

agarose hydrogel stamps; cell orientation; electrospun nanofibers; microcontact printing; microfluidic devices

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sefarose / Hidrogel de Polietilenoglicol-Dimetacrilato / Nanotecnologia / Dispositivos Lab-On-A-Chip / Nanofibras / Células-Tronco Mesenquimais Limite: Animals / Humans Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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