Epidemiology of Zika.
Curr Opin Pediatr
; 29(1): 97-101, 2017 02.
Article
em En
| MEDLINE
| ID: mdl-27845968
ABSTRACT
PURPOSE OF REVIEW Zika virus (ZIKV) is the latest 'emerging virus' that has affected the Americas. First identified in the mid-20th century in Uganda, it was described as a vector arthropod-borne virus (arbovirus) and subsequently found capable of producing illness in humans. The illness was not different from other flavivirus infections and caused a relatively mild disease characterized by low-grade fever, nonspecific exanthem, nonpurulent conjunctivitis, and mild to moderate arthralgia. It was capable of producing infections described as sporadic isolated cases; in 2007, it was confirmed as the pathogen causing the first known ZIKV epidemic subsequently associated with congenital neonatal microcephaly in many countries in the Americas. RECENT FINDINGS:
It rapidly spread to other countries in the Americas and, as of September 2016, it has been detected in 46 countries and territories. Different from other flavivirus infections, ZIKV has proven to be related to more serious complications. These include Guillain-Barré syndrome and neonatal congenital malformations, which includes microcephaly and neurologic damage to the developing fetus, particularly if the maternal infection occurs early in pregnancy. These two complications are a cause of great concern.SUMMARY:
It is pivotal to conduct epidemiological laboratory-based surveillance and studies on the virus' inherent characteristics to understand the pathophysiology of this infection and develop adequate strategies to mitigate this new threat.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecção por Zika virus
Tipo de estudo:
Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Curr Opin Pediatr
Assunto da revista:
PEDIATRIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos