Functional affinity of antibody to the Haemophilus influenzae type b polysaccharide.
J Infect Dis
; 159(6): 1083-7, 1989 Jun.
Article
em En
| MEDLINE
| ID: mdl-2786040
ABSTRACT
The functional affinity, or avidity, of antibody to the capsular polysaccharide of Haemophilus influenzae (Hib-PS) was measured in serum samples from 12 adult male subjects before and after immunization with Hib-PS vaccine. Mean avidity increased from 0.74 nM-1 to 1.5 nM-1 after immunization (P less than .05, paired Student's t test). The Bureau of Biologics reference antiserum had an avidity constant of 12 nM-1, which was the highest of all 25 serum samples studied.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polissacarídeos Bacterianos
/
Vacinas Bacterianas
/
Haemophilus influenzae
/
Vacinas Anti-Haemophilus
/
Anticorpos Antibacterianos
Limite:
Humans
/
Male
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
1989
Tipo de documento:
Article