Anti-factor VIII antibodies in brothers with haemophilia A share similar characteristics.

Kahle, J; Orlowski, A; Stichel, D; Healey, J F; Parker, E T; Donfield, S M; Astermark, J; Berntorp, E; Lollar, P; Schwabe, D; Königs, C

Kahle, J; Orlowski, A; Stichel, D; Healey, J F; Parker, E T; Donfield, S M; Astermark, J; Berntorp, E; Lollar, P; Schwabe, D; Königs, C.

Afiliação

Kahle J; Department of Paediatrics, Clinical and Molecular Haemostasis and Immunodeficiency, University Hospital Frankfurt, Frankfurt am Main, Germany.
Orlowski A; Department of Paediatrics, Clinical and Molecular Haemostasis and Immunodeficiency, University Hospital Frankfurt, Frankfurt am Main, Germany.
Stichel D; Department of Paediatrics, Clinical and Molecular Haemostasis and Immunodeficiency, University Hospital Frankfurt, Frankfurt am Main, Germany.
Healey JF; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, GA, USA.
Parker ET; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, GA, USA.
Donfield SM; Department of Biostatistics, Rho Inc., Chapel Hill, NC, USA.
Astermark J; Centre for Thrombosis and Haemostasis, Lund University, Skåne University Hospital, Malmö, Sweden.
Berntorp E; Centre for Thrombosis and Haemostasis, Lund University, Skåne University Hospital, Malmö, Sweden.
Lollar P; Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, GA, USA.
Schwabe D; Department of Paediatrics, Clinical and Molecular Haemostasis and Immunodeficiency, University Hospital Frankfurt, Frankfurt am Main, Germany.
Königs C; Department of Paediatrics, Clinical and Molecular Haemostasis and Immunodeficiency, University Hospital Frankfurt, Frankfurt am Main, Germany.

Haemophilia ; 23(2): 292-299, 2017 Mar.

Article em En | MEDLINE | ID: mdl-27862687

Assuntos

Anticorpos/sangue; Fator VIII/uso terapêutico; Hemofilia A/tratamento farmacológico; Fator VIII/administração & dosagem; Hemofilia A/imunologia; Humanos; Masculino; Irmãos

Palavras-chave

IgG subclasses; anti-factor VIII antibodies; epitope mapping; factor VIII inhibitors; haemophilia A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator VIII / Hemofilia A / Anticorpos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Haemophilia Assunto da revista: HEMATOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

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