Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer.

Xiao, T; Zhu, J J; Huang, S; Peng, C; He, S; Du, J; Hong, R; Chen, X; Bode, A M; Jiang, W; Dong, Z; Zheng, D

Xiao, T; Zhu, J J; Huang, S; Peng, C; He, S; Du, J; Hong, R; Chen, X; Bode, A M; Jiang, W; Dong, Z; Zheng, D.

Afiliação

Xiao T; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Zhu JJ; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Huang S; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Peng C; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
He S; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Du J; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Hong R; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Chen X; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Bode AM; Hormel Institute, University of Minnesota, Austin, MN, USA.
Jiang W; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.
Dong Z; Hormel Institute, University of Minnesota, Austin, MN, USA.
Zheng D; Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, People's Republic of China.

Oncogene ; 36(20): 2835-2845, 2017 05 18.

Article em En | MEDLINE | ID: mdl-27893713

Assuntos

Transformação Celular Neoplásica/metabolismo; Quinase 3 Dependente de Ciclina/metabolismo; Fatores de Transcrição NFATC/metabolismo; Neoplasias Cutâneas/metabolismo; Neoplasias Cutâneas/patologia; Animais; Linhagem Celular Tumoral; Proliferação de Células; Transformação Celular Neoplásica/genética; Quinase 3 Dependente de Ciclina/química; Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Humanos; Camundongos; Fatores de Transcrição NFATC/genética; Proteínas Oncogênicas/genética; Proteínas Oncogênicas/metabolismo; Fosforilação; Regiões Promotoras Genéticas; Ligação Proteica; Neoplasias Cutâneas/genética; Especificidade por Substrato; Ativação Transcricional

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Transformação Celular Neoplásica / Fatores de Transcrição NFATC / Quinase 3 Dependente de Ciclina Limite: Animals / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article

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