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An α/ß-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization.
Zheng, Qingfei; Wang, Shoufeng; Duan, Panpan; Liao, Rijing; Chen, Dandan; Liu, Wen.
Afiliação
  • Zheng Q; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China.
  • Wang S; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China.
  • Duan P; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China.
  • Liao R; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China.
  • Chen D; State Key Laboratory of Microbial Metabolism, School of Life Science & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
  • Liu W; Huzhou Center of Bio-Synthetic Innovation, Huzhou 313000, China.
Proc Natl Acad Sci U S A ; 113(50): 14318-14323, 2016 12 13.
Article em En | MEDLINE | ID: mdl-27911800
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioestreptona / Hidrolases Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioestreptona / Hidrolases Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China