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Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.
Chu, Fong-Fong; Esworthy, R Steven; Doroshow, James H; Grasberger, Helmut; Donko, Agnes; Leto, Thomas L; Gao, Qiang; Shen, Binghui.
Afiliação
  • Chu FF; Department of Gastroenterology and Hepatology, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan 471003, China; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA;
  • Esworthy RS; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
  • Doroshow JH; Center for Cancer Research and Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
  • Grasberger H; Department of Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
  • Donko A; National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
  • Leto TL; National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
  • Gao Q; Department of Gastroenterology and Hepatology, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan 471003, China.
  • Shen B; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Redox Biol ; 11: 144-156, 2017 04.
Article em En | MEDLINE | ID: mdl-27930931
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Oxidases Duais / NADPH Oxidase 1 / Ileíte / Inflamação Tipo de estudo: Incidence_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Redox Biol Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Oxidases Duais / NADPH Oxidase 1 / Ileíte / Inflamação Tipo de estudo: Incidence_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Redox Biol Ano de publicação: 2017 Tipo de documento: Article