3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".

Choi, Se Hoon; Kim, Young Hye; Quinti, Luisa; Tanzi, Rudolph E; Kim, Doo Yeon

Choi, Se Hoon; Kim, Young Hye; Quinti, Luisa; Tanzi, Rudolph E; Kim, Doo Yeon.

Afiliação

Choi SH; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, 02129, Charlestown, MA, USA.
Kim YH; Biomedical Omics Group, Korea Basic Science Institute, Cheongju-si, Chungbuk, 363-883, Republic of Korea.
Quinti L; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, 02129, Charlestown, MA, USA.
Tanzi RE; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, 02129, Charlestown, MA, USA. tanzi@helix.mgh.harvard.edu.
Kim DY; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, 02129, Charlestown, MA, USA. dkim@helix.mgh.harvard.edu.

Mol Neurodegener ; 11(1): 75, 2016 12 09.

Article em En | MEDLINE | ID: mdl-27938410

Assuntos

Doença de Alzheimer; Técnicas de Cultura de Células; Células-Tronco Neurais/citologia; Humanos

Palavras-chave

Alzheimer's disease; Amyloid plaques; High-throughput drug screening; Induced-pluripotent stem cell; Neurofibrillary tangles; Three-dimensional culture

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Cultura de Células / Células-Tronco Neurais / Doença de Alzheimer Limite: Humans Idioma: En Revista: Mol Neurodegener Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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